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Invitrogen™ Langerin Polyclonal Antibody
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Catalog No. PIPA547250
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100 μg
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Catalog No. Quantity
PIPA547250 100 μg
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Catalog No. PIPA547250 Supplier Invitrogen™ Supplier No. PA547250
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Description

Goat Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Langerin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CD207
Gene Accession No. Q9UJ71
Gene Alias CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913
Gene Symbols CD207
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human Langerin/CD207 Tyr64-Pro328.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50489
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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