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Invitrogen™ Lano Polyclonal Antibody
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Catalog No. PIPA583199
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100 μL
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PIPA583199 100 μL
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Catalog No. PIPA583199 Supplier Invitrogen™ Supplier No. PA583199
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QSLPENIGNL YNLASLELRE NLLTYLPDSL TQLRRLEELD LGNNEIYNLP ESVGALLHLK DLWLDGNQLS ELPQEIGNLK NLLCL Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 96%.

Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lano
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LRRC1
Gene Accession No. Q9BTT6
Gene Alias A430093J20Rik; AU016091; D030059I21; dJ523E19.1; LANO; LANO adapter protein; LAP (leucine-rich repeats and PDZ) and no PDZ protein; LAP and no PDZ protein; leucine rich repeat containing 1; leucine-rich repeat-containing 1; leucine-rich repeat-containing protein 1; LRRC1; mKIAA4018; RP3-523E19.1
Gene Symbols LRRC1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LRRC1. Recombinant protein control fragment (Product #RP-94871).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55227
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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