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Invitrogen™ Lano Polyclonal Antibody
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Catalog No. PIPA519994
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100 μg
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Catalog No. Quantity
PIPA519994 100 μg
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Catalog No. PIPA519994 Supplier Invitrogen™ Supplier No. PA519994
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Description

Rabbit Polyclonal Antibody

A suggested positive control is PC-3 cell lysate. PA5-19994 can be used with blocking peptide PEP-0116.

Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ (PSD95/DLG/ZO-1) domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lano
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene LRRC1
Gene Accession No. Q9BTT6
Gene Alias A430093J20Rik; AU016091; D030059I21; dJ523E19.1; LANO; LANO adapter protein; LAP (leucine-rich repeats and PDZ) and no PDZ protein; LAP and no PDZ protein; leucine rich repeat containing 1; leucine-rich repeat-containing 1; leucine-rich repeat-containing protein 1; LRRC1; mKIAA4018; RP3-523E19.1
Gene Symbols LRRC1
Host Species Rabbit
Immunogen A peptide corresponding to 15 amino acids near the carboxy terminus of human Lano.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55227
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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