Invitrogen™ LAP (Latency Associated Peptide) Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5143311

Catalog No. PIPA5143311

Description

Additional Information: This antibody is expected to recognize the part representing the latency-associated peptide. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.

Specifications

• Antigen: LAP (Latency Associated Peptide)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TGFB1
• Gene Alias: CED; DPD1; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; Tgfb1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 7040
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P01137
• Gene Symbols: TGFB1
• Immunogen: Peptide with sequence C-STYTSGDQKTIKSTR (aa 257-271).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG