Learn More
LAP (Latency Associated peptide) Monoclonal Antibody (FNLAP), PE-Cyanine7, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$434.00
Specifications
Antigen | LAP (Latency Associated peptide) |
---|---|
Clone | FNLAP |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-245-760
|
Invitrogen
25982942 |
100 Tests |
Each of 1 for $434.00
|
|
|||||
Description
Description: The FNLAP monoclonal antibody reacts with human latency associated peptide (LAP, pro-TGF beta 1, LAP/TGF beta 1). Many different cells produce TGF beta and it mediates effects on the proliferation, differentiation and function of many cell types. TGF beta is synthesized as a precursor that contains LAP at the N-terminus and mature TGF beta at the C-terminus. Processing and cleavage of the precursor protein between amino acids 278 and 279 results in the formation of LAP dimers and TGF beta dimers that then non-covalently associate with each other to form the small latent TGF beta complex. LAP is secreted and can be found in the extracellular matrix. In addition, LAP can also be expressed on platelets and activated regulatory T cells. It is believed that this surface-expressed LAP is due to the binding of LAP to GARP (LRRC32), which is a transmembrane protein that is also found at high levels on platelets and activated regulatory T cells. Applications Reported: This FNLAP antibody has been reported for use in flow cytometric analysis. Applications Tested: This FNLAP antibody has been pre-titrated and tested by flow cytometric analysis of stimulated human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.
LAP (Latency Associated peptide) Monoclonal antibody specifically detects LAP (Latency Associated peptide) in Human samples. It is validated for Flow Cytometry.Specifications
LAP (Latency Associated peptide) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
P01137 | |
TGFB1 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
TGFB1 |
FNLAP | |
Flow Cytometry | |
PE-Cyanine7 | |
Mouse | |
Human | |
7040 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.