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Invitrogen™ LAR4B Polyclonal Antibody
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Catalog No. PIPA565339
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100 μL
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PIPA565339 100 μL
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Catalog No. PIPA565339 Supplier Invitrogen™ Supplier No. PA565339
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRKPSYAEICQ RTSKEPPSSP LQPQKEQKPN TVGCGKEEKK LAEPAERYRE PPALKSTPGA PRDQRRPAGG RPSPSAMGKR LSR Highest antigen sequence identity to the following orthologs - mouse 78%, rat 87%.

The LAR4B gene, more accurately referred to as LARP4B (La Ribonucleoprotein Domain Family Member 4B), is associated with RNA-binding proteins that are crucial for various aspects of RNA metabolism, including RNA stabilization, translation, and cellular stress responses. LARP4B belongs to the La-related protein family, which plays significant roles in maintaining RNA stability and enhancing translation efficiency of certain mRNAs. It has been identified as a target in cancer research due to its involvement in tumor biology, particularly regulating tumor suppressive pathways and interacting with microRNA networks. Studies have shown that LARP4B expression is downregulated in prostate cancer tissues, indicating its potential role as a tumor suppressor. Moreover, it is linked with liver cancer and survival rates, reflecting its importance in cellular growth and proliferation. The regulation of LARP4B and its interactions with other cellular components underline its potential therapeutic implications for cancer treatment.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LAR4B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LARP4B
Gene Accession No. Q92615
Gene Alias A630096F19; AI256361; D13Wsu64e; KIAA0217; La ribonucleoprotein 4B; La ribonucleoprotein domain family member 4B; La ribonucleoprotein domain family member 5; La ribonucleoprotein domain family, member 4B; La ribonucleoprotein domain family, member 5; la-related protein 4B; La-related protein 5; LARP4B; Larp5; RGD1310713
Gene Symbols LARP4B
Host Species Rabbit
Immunogen Recombinant Human LAR4B. Recombinant protein control fragment (Product #RP-104757).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23185
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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