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Invitrogen™ LARGE Polyclonal Antibody
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Catalog No. PIPA519292
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100 μg
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Catalog No. Quantity
PIPA519292 100 μg
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Catalog No. PIPA519292 Supplier Invitrogen™ Supplier No. PA519292
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine and canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.

The LARGE gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LARGE
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Large1
Gene Accession No. O95461
Gene Alias Acetylglucosaminyltransferase-like 1A; acetylglucosaminyltransferase-like protein; Beta-1,3-glucuronyltransferase LARGE; BPFD#36; enr; eosinophil granule major basic protein 1; fg; froggy; glycosyltransferase-like 1A; Glycosyltransferase-like protein; glycosyltransferase-like protein LARGE1; glycosyltransferase-like protein LARGE1; LARGE xylosyl- and glucuronyltransferase 1; Gyltl1a; KIAA0609; large; LARGE xylosyl- and glucuronyltransferase 1; Large1; like-acetylglucosaminyltransferase; like-glycosyltransferase; MBP1; Mbp-1; MDC1D; MDDGA6; MDDGB6; mKIAA0609; myd; myodystrophy; prepro major basic protein 1; Xylosyltransferase LARGE
Gene Symbols Large1
Host Species Goat
Immunogen Synthetic peptide sequence (SEADVNSENLQKQ) corresponding to the internal amino acids of LARGE (aa 421-434).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9215
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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