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Invitrogen™ LARGE Polyclonal Antibody
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Catalog No. PIPA578393
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100 μL
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PIPA578393 100 μL
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Catalog No. PIPA578393 Supplier Invitrogen™ Supplier No. PA578393
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Description

Rabbit Polyclonal Antibody

Positive Control: mouse liver Predicted Reactivity: Human (100%), Rhesus Monkey (100%), Bovine (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The LARGE gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LARGE
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Large1
Gene Accession No. O95461, Q9Z1M7
Gene Alias Acetylglucosaminyltransferase-like 1A; acetylglucosaminyltransferase-like protein; Beta-1,3-glucuronyltransferase LARGE; BPFD#36; enr; eosinophil granule major basic protein 1; fg; froggy; glycosyltransferase-like 1A; Glycosyltransferase-like protein; glycosyltransferase-like protein LARGE1; glycosyltransferase-like protein LARGE1; LARGE xylosyl- and glucuronyltransferase 1; Gyltl1a; KIAA0609; large; LARGE xylosyl- and glucuronyltransferase 1; Large1; like-acetylglucosaminyltransferase; like-glycosyltransferase; MBP1; Mbp-1; MDC1D; MDDGA6; MDDGB6; mKIAA0609; myd; myodystrophy; prepro major basic protein 1; Xylosyltransferase LARGE
Gene Symbols Large1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human LARGE. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16795, 361368, 9215
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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