LARP1 Rabbit anti-Drosophila, Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 137081AP150UL

Catalog No. 50-172-8948

Description

RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5′cap in an MTOR-dependent manner and associates with mRNAs containing a 5′ terminal oligopyrimidine (5′TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5′TOP, thereby regulating cell growth and proliferation. Positively regulates the replication of dengue virus (DENV).

Specifications

• Antigen: LARP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LARP1
• Gene Alias: KIAA0731, La related protein 1, LARP, LARP1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23367, 303158, 53567, 73158
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.51 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6PKG0, Q6ZQ58
• Gene Symbols: larp, Larp1
• Immunogen: LARP1 Fusion Protein Ag4645
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Drosophila, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG