Invitrogen™ LAS1L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563962

Catalog No. PIPA563962

Description

Immunogen sequence: VRWDTFPLGR MPGQTEDPAE LMLENYDTMY LLDQPVLEQR LEPSTCKTDT LGLSCGVGSG NCSNSSSSNF EGLLWSQGQL HGLKTG Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 67%.

Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Specifications

• Antigen: LAS1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Las1l
• Gene Alias: 1810030A06Rik; 5830482G23Rik; dJ475B7.2; LAS1 like ribosome biogenesis factor; LAS1 like, ribosome biogenesis factor; LAS1L; Las1-like; LAS1-like (S. cerevisiae); LAS1-like, ribosome biogenesis factor; MSTP060; Protein LAS1 homolog; RGD1565755; Ribosomal biogenesis protein LAS1L
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 81887
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y4W2
• Gene Symbols: Las1l
• Immunogen: Recombinant protein corresponding to Human LAS1L. Recombinant protein control fragment (Product #RP-103404).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG