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LAT Mouse anti-Human, Clone: LAT1111, Abnova™

Catalog No. 89934458 Shop All Abnova Corporation Products
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89-934-458 50 μg
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Catalog No. 89-934-458 Supplier Abnova Corporation Supplier No. MAB12960
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Description

Mouse monoclonal antibody raised against recombinant human LAT.

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Specifications

Antigen LAT
Applications Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone LAT1111
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant human LAT.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (0.09% sodium azide).
Gene Alias LAT1/pp36
Gene Symbols LAT
Host Species Mouse
Immunogen Recombinant protein corresponding to cytoplasmic domain of human LAT.
Purification Method Affinity purification
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27040
Target Species Human
Content And Storage Store at 4°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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