LATH Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-2531	Proteintech Group Inc 197631AP150UL	150 μL

Description

The PLUNC family of proteins are encoded by genes which map to chromosome 20 and are thought to play a potential role in the innate immune response in regions of the mouth, nose and lungs. As a member of the PLUNC family, BASE (breast cancer and salivary gland-expressed protein) is a 179 amino acid secreted protein that is named for its expression pattern. Due to its 63% sequence similarity with the related protein, Latherin, it is suggested that BASE is the major protein in sweat secretions and has important surfactant properties that lower surface tension. The expression pattern of BASE in many breast cancer cell lines suggests that it may be an easily accessible diagnostic breast cancer marker. Due to the fact that the gene encoding BASE is highly estrogen-repressed, expression of the gene is most likely dependent on HNF-3alpha and estrogen-mediated repression requiring ERalpha.

Specifications

• Antigen: LATH
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q86YQ2
• Gene ID (Entrez): 317716
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: BPIFA4P

• Concentration: 0.29 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: BASE, LATH, Latherin, RP11 49G10.8, RP11-49G10.8
• Gene Symbols: BPIFA4P
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody