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Tocris Bioscience™ Laulimalide

Catalog No. 400710U
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10 μg
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Catalog No. Quantity
40-071-0U 10 μg
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Catalog No. 40-071-0U Supplier Tocris Bioscience™ Supplier No. 4007/10U
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Description

Microtubule stabilzing agent

Laulimalide is a microtubule stabilizing agent. Potent inhibitor of cellular proliferation in cancer cell lines (IC50 reported to be 3-30 nM, dependent on cell line used). Causes cells to arrest in the prometaphase of the cell cycle, prevents formation of bipolar spindle and increases kinetochore tension in preformed spindles.

Specifications

Chemical Name or Material (1R,3S,7S,8S,10S,12S,15Z,18R)-12-[(1S,2E)-3-[(2S)-3,6-dihydro-4-methyl-2H-pyran-2-yl]-1-hydroxy-2-propen-1-yl]-7-hydroxy-3-methyl-5-methylene-9,13,22-trioxatricyclo[16.3.1.08,10]docosa-15,19-dien-14-one
CAS 115268-43-4
Quantity 10 μg
Molecular Formula C30H42O7
Purity 97%
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