Invitrogen™ Layilin Monoclonal Antibody (07)

Catalog No.	Quantity
PIMA531020	100 μL

Catalog No. PIMA531020

Supplier: Invitrogen™ MA531020

Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Layilin /LAYN.

Layilin is a cell surface receptor encoded by the LAYN gene, known for its involvement in cell adhesion and motility processes. It is a member of the C-type lectin-like domain protein family and plays a crucial role in mediating interactions with the extracellular matrix. Layilin is associated with cytoskeletal reorganization, impacting cellular processes such as shape change, migration, and stabilization of cell-matrix contacts. It has been shown to interact with other proteins like talin, contributing to the linkage between the cell membrane and the actin cytoskeleton, which is vital for maintaining cell structure and facilitating movement. Layilin's role in cell adhesion and motility makes it significant in developmental processes and wound healing. Additionally, dysregulation of layilin expression has been implicated in cancer metastasis, where altered adhesive properties and increased motility contribute to tumor progression and dissemination. Research is ongoing to explore the detailed mechanisms of layilin's function and its potential as a target for therapeutic intervention in diseases characterized by abnormal cell migration and adhesion.

Specifications

• Antigen: Layilin
• Applications: ELISA
• Classification: Monoclonal
• Clone: 07
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: LAYN
• Gene Accession No.: Q6UX15
• Gene Alias: E030012M19Rik; FLJ30977; FLJ31092; Gm511; layilin; LAYN; LYAN; RGD1564444; UNQ208/PRO234
• Gene Symbols: LAYN
• Host Species: Mouse
• Immunogen: Recombinant Human Layilin/LAYN Protein (Met1-Glu220).
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 143903
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid