Invitrogen™ LBP Monoclonal Antibody (1C7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA140130

Catalog No. 01-676-521

Description

MA1-40130 detects LBP from human samples. MA1-40130 has been successfully used in ELISA,functional assays and immunoprecipitation applications. ELISA: monoclonal antibody 1C7 can be used both as coating and as detector. The MA1-40130 immunogen is the LPS binding site on LBP. Endotoxin <24 EU/mg.

The LBP protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.

Specifications

• Antigen: LBP
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% BSA and no preservative
• Gene Accession No.: P18428
• Gene Symbols: LBP
• Immunogen: LPS binding site on LBP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Functional Assay, Immunoprecipitation
• Clone: 1C7
• Conjugate: Unconjugated
• Gene: LBP
• Gene Alias: acute phase protein; binds bacterial LPS; BPI fold containing family D, member 2; Bpifd2; hypothetical protein LOC512242; LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; lipopolysaccharide-binding protein LPSBP; LPS-binding protein; LPSBP; Ly88
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3929
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

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