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Invitrogen™ LCAT Polyclonal Antibody
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Catalog No. PIPA522965
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100 μL
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PIPA522965 100 μL
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Catalog No. PIPA522965 Supplier Invitrogen™ Supplier No. PA522965
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Description

Rabbit Polyclonal Antibody

Suggested positive control: antigen standard for LCAT (transient overexpression lysate), Lipoprotein fraction of whole mouse plasma.

Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LCAT
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.05% sodium azide
Gene LCAT
Gene Accession No. P04180, P16301
Gene Alias AI046659; D8Wsu61e; Lcat; lecithin cholesterol acyltransferase; lecithin-cholesterol acyltransferase; lecithin-cholesterol acyltransferase Lcat; phosphatidylcholine-sterol acyltransferase; phosphatidylcholine--sterol O-acyltransferase; Phospholipid-cholesterol acyltransferase; testicular secretory protein Li 24
Gene Symbols LCAT
Host Species Rabbit
Immunogen Carboxyl-terminal histidine-tagged mouse recombinant LCAT purified from the medium of CHO cells overexpressing mouse LCAT cDNA.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16816, 3931
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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