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Invitrogen™ LCAT Polyclonal Antibody
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Catalog No. PIPA588243
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100 μL
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PIPA588243 100 μL
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Catalog No. PIPA588243 Supplier Invitrogen™ Supplier No. PA588243
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: FWLLNVLFPP HTTPKAELSN HTRPVILVPG CLGNQLEAKL DKPDVVNWMC YRKTEDFFTI WLDLNMFLPL GVDCWIDNTR VVYNRSSGLV SNAPGVQIRV PGFGKTYSVE YLDSSKLAGY LHTLVQNLVN NGYVRDETVR AAPYDWRLEP GQQEEYYRKL AGLVEEMHAA YGKPVFLIGH SLGCLHLLYF LLRQPQAWKD RFIDGFISLG APWGGSIKPM LVLASGDNQG IPIMSSIKLK EEQRITTTSP WMFPSRMAWP EDHVFISTPS FNYTGRDFQR FFADLHFEEG WYMWLQSRDL LAGLPAPGVE VYCLYGVGLP TPRTYIYDHG FPYTDPVGVL YEDGDDTVAT RSTELCGLWQ GRQPQPVHLL PLHGIQHLNM VFSNLTLEHI NAILLGAYRQ GPPASPTASP EPPPPE; Positive Samples: Mouse brain.

Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LCAT
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene LCAT
Gene Accession No. P16301
Gene Alias AI046659; D8Wsu61e; Lcat; lecithin cholesterol acyltransferase; lecithin-cholesterol acyltransferase; lecithin-cholesterol acyltransferase Lcat; phosphatidylcholine-sterol acyltransferase; phosphatidylcholine--sterol O-acyltransferase; Phospholipid-cholesterol acyltransferase; testicular secretory protein Li 24
Gene Symbols LCAT
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 25-440 of human LCAT (NP_0002201).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16816
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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