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  5. Tocris Bioscience™ LCB 03-0110 dihydrochloride

Tocris Bioscience™ LCB 03-0110 dihydrochloride
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Catalog No. 559250
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559250 50 mg
559210 10 mg
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Catalog No. 559250 Supplier Tocris Bioscience™ Supplier No. 5592/50
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Description

Potent c-SRC kinase inhibitor; also inhibits DDR2, BTK and Syk

LCB 03-0110 dihydrochloride is a potent c-Src kinase inhibitor (IC50 = 1.3 nM). Also potent inhibitor of discoidin domain receptor 2 (DDR2) family tyrosine kinases, BTK and Syk. Suppresses LPS-induced activation of macrophages and TGF-β1- induced activation of fibroblasts in vitro. Also inhibits activation of macrophages and fibroblasts and suppresses scar formation in a wound healing model.

Specifications

Chemical Name or Material 3-[[2-[3-(4-Morpholinylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenol dihydrochloride
Quantity 50 mg
Target Src Family Kinase Inhibitors
Molecular Formula C24H23N3O2S.2HCl
Formula Weight 490.45
Purity >98%
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