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Invitrogen™ LCLAT1 Polyclonal Antibody
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Catalog No. PIPA556886
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100 μL
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PIPA556886 100 μL
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Catalog No. PIPA556886 Supplier Invitrogen™ Supplier No. PA556886
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Rabbit Polyclonal Antibody

Immunogen sequence: LHPRTTGFTF VVDRLREGKN LDAVHDITVA YPHNIPQSEK HLLQGDFPRE IHFHVHRYPI DTLPTSKEDL QLWCHKR Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%.

Exhibits acyl-CoA:lysocardiolipin acyltransferase (ALCAT) activity; catalyzes the reacylation of lyso-cardiolipin to cardiolipin (CL), a key step in CL remodeling. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Also exhibits 1-acyl-sn-glycerol-3-phosphate acyltransferase activity (AGPAT) activity; converts 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3- phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:16620771). Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities (PubMed:19075029). Required for establishment of the hematopoietic and endothelial lineages. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen LCLAT1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LCLAT1
Gene Accession No. Q6UWP7
Gene Alias 1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; Acyl-CoA:lysocardiolipin acyltransferase 1; Agpat8; AI181996; Alcat1; Gm91; HSRG1849; LCLAT1; Lycat; lysocardiolipin acyltransferase 1; RGD1565906; UNQ1849; UNQ1849/PRO3579
Gene Symbols LCLAT1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LCLAT1. Recombinant protein control fragment (Product #RP-95708).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 253558
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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