Invitrogen™ LDB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530685

Catalog No. PIPA530685

Description

Recommended positive controls: NT2D1, mouse brain. Predicted reactivity: Mouse (95%), Rat (96%), Chicken (95%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Genes encoding LIM domain-binding factors were initially isolated in a screen for proteins that physically interact with the LIM domains of nuclear proteins. These proteins, such as the one encoded by the LDB2 gene, are capable of binding to a variety of transcription factors and are likely to function at enhancers to bring together diverse transcription factors and form higher order activation complexes or to block formation of such complexes. The family of genes encoding LIM domain-binding factors includes 2 members isolated from the mouse, Clim1 and Clim2/Lbd1/Nli; and their homologs cloned from the frog, chicken, and fly. The fact that LIM domain-binding factors are likely to be involved in the coordination of the transcriptional activity of many diverse factors might implicate them in human phenotypes characterized by multiple affected sites.

Specifications

• Antigen: LDB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LDB2
• Gene Alias: AI035351; AW146358; Carboxyl-terminal LIM domain-binding protein 1; cLdb2; Clim1; CLIM-1; CLP-36; LDB1; Ldb2; LDB-2; Ldb3; LIM binding domain 2; LIM domain binding 2; LIM domain binding protein CLIM-1; LIM domain-binding factor CLIM1; LIM domain-binding factor-2; LIM domain-binding protein 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16826, 9079
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.39 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O43679, O55203
• Gene Symbols: LDB2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 90 and 334 of Human LDB2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG