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Invitrogen™ LDB3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA577222
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.
Specifications
LDB3 | |
Polyclonal | |
Unconjugated | |
LDB3 | |
AW742271; cardiomyopathy, dilated 1C (autosomal dominant); CMD1C; CMH24; CMPD3; cypher; FLJ35865; HGNC:15710; KIAA01613; KIAA0613; LDB3; LDB3Z1; LDB3Z4; LIM domain binding 3; LIM domain-binding protein 3; LVNC3; MFM4; ORACLE; oracle protein; PDLIM6; PDZ and LIM domain 6; PDZ-LIM domain protein; protein cypher; Protein oracle; RGD1564875; ZASP; Z-band alternatively spliced PDZ motif protein; Z-band alternatively spliced PDZ-motif protein | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
11155, 24131, 498587 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
O75112, Q9JKS4 | |
LDB3 | |
Recombinant full length Human LDB3. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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