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LDHA Mouse anti-Human, Clone: OTI2D11, liquid, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA500568

Encompass_Preferred

Catalog No. 50-167-1706


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Description

Description

Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84-89% sequence similarities and 69-75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers.
Specifications

Specifications

LDHA
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P00338
LDHA
Full length human recombit protein of human LDHA produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
OTI2D11
Unconjugated
LDHA
GSD11, HEL-S-133P, LDHM, PIG19
Mouse
Affinity Chromatography
RUO
3939
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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