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Tocris Bioscience™ LDN 193189 in solution

Catalog No. 81506
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Quantity:
6 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Sterile-filtered 10 mM solution of LDN 193189 pre-dissolved in water

LDN 193189 in solution is a convenient and ready-to-use 10 mM sterile-filtered solution of LDN 193189 pre-dissolved in water. A potent and selective ALK2 and ALK3 inhibitor (IC50 values are 5 nM and 30 nM, respectively); inhibits BMP4-mediated Smad1/5/8 activation. Promotes neural induction of hPSCs in combination with SB 431542 (Cat. No. 1614). Also induces differentiation of hPSCs into nociceptive sensory neurons in combination with SB 431542 (Cat. No. 1614), SU 5402 (Cat. No. 3300), CHIR 99021 (Cat. No. 4423) and DAPT (Cat. No. 2634).

Specifications

Chemical Name or Material 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
CAS 1435934-00-1
Quantity 6 mg
Target BMP and Other Activin Receptor Inhibitors
Molecular Formula C25H22N6.2HCl
Purity 0.97
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