Invitrogen™ LDOC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541537

Catalog No. PIPA541537

Description

Peptide sequence: MVDELVLLLH ALLMRHRALS IENSQLMEQL RLLVCERASL LRQVRPPSCP Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Rabbit: 100%; Rat: 79%.

LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Specifications

• Antigen: LDOC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ldoc1
• Gene Alias: 7-Mar; BCUR1; breast cancer, up-regulated 1; Gm366; Ldoc1; LDOC1 regulator of NFKB signaling; LDOC1, regulator of NFKB signaling; Leucine zipper; leucine zipper downregulated in cancer; leucine zipper down-regulated in cancer 1; leucine zipper protein down-regulated in cancer cells; leucine zipper, down-regulated in cancer 1; Mar7; Mart7; Protein LDOC1; RGD1565644
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23641
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O95751
• Gene Symbols: Ldoc1
• Immunogen: Synthetic peptide directed towards the N-terminal of human LDOC1 (aa 1-50).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov