Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA552698

Invitrogen™ LECT1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA552698
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA552698 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA552698 Supplier Invitrogen™ Supplier No. PA552698
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: NGITGIRFAG GEKCYIKAQV KARIPEVGAV TKQSISSKLE GKIMPVKYEE NSLIWVAVDQ PVKDNSFLSS KVLELCGDLP IFWLKPTYPK EIQRERREVV RKIVPTTTKR PHSGPRSNPG AGRLNNETRP SVQ Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.

ChM-1 is a cartilage-specific matrix glycoprotein that stimulates the growth of chondrocytes. ChM-1 inhibits angiogenesis by disrupting the tube formation of endothelial cells and thus is responsible for the avascular nature of cartilage. ChM-1 is strongly expressed by the proliferating and hypertrophic zones in the epiphyseal plate of long bones. ChM-1 accumulates in the interterritorial matrix around the lacunae. During development, downregulation of ChM-1 permits angiogenesis and ultimately bone formation on the cartilage template. ChM-1 expression is downregulated in the presence of several growth factors including TGFβ2, FGF2 and PTHLH. ChM-1 expression may also play a role in the hypovascularity and chondroid formation of pleomorphic adenomas. The gene encoding human ChM-1 maps to chromosome 13q14-q21.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LECT1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CNMD
Gene Accession No. O75829
Gene Alias BRICD3; BRICHOS domain containing 3; CHM1; Chm-1; Chmi; CHM-I; Chondromodulin; Chondromodulin 1; chondromodulin I; chondromodulin-1; Chondromodulin-I; Chondrosurfactant protein; CH-SP; Cnmd; LECT1; leukocyte cell derived chemotaxin 1; leukocyte cell-derived chemotaxin 1; multiple myeloma tumor suppressor 1; MYETS1
Gene Symbols CNMD
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LECT1. Recombinant protein control fragment (Product #RP-90242).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11061
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.