LEDGF/p75 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A300848AT
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine and CatTranscriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.
|TBS with 0.1% BSA and 0.09% sodium azide|
|Between 480 and C-term|
|CLL-associated antigen KW-7, dense fine speckles 70 kDa protein, DFS 70, DFS70, LEDGF, lens epithelium-derived growth factor, p52, p75, PAIP, PC4 and SFRS1 interacting protein 2, PSIP2, transcriptional coactivator p52/p75, Transcriptional coactivator p75/p52|
|Antigen affinity chromatography|
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