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LEDGF/p75 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501558605
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50-155-8605 100 μL
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Catalog No. 50-155-8605 Supplier Bethyl Laboratories, Inc Supplier No. A300848A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine and Cat

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.

Specifications

Antigen LEDGF/p75
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PSIP1
Gene Accession No. O75475
Gene Alias CLL-associated antigen KW-7, dense fine speckles 70 kDa protein, DFS 70, DFS70, LEDGF, lens epithelium-derived growth factor, p52, p75, PAIP, PC4 and SFRS1 interacting protein 2, PSIP2, transcriptional coactivator p52/p75, Transcriptional coactivator p75/p52
Gene Symbols PSIP1
Host Species Rabbit
Immunogen Between 480 and C-term
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11168
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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