LEF1 Monoclonal Antibody (REMB1), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA112418

Catalog No. 01-674-296

Description

A suggested positive control for this product is Jurkat cell lysate.

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: LEF1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: P27782, Q9UJU2
• Gene Symbols: LEF1
• Immunogen: Full length recombinant LEF-1 protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: REMB1
• Conjugate: Unconjugated
• Gene: LEF1
• Gene Alias: 3000002B05; AI451430; DKFZp586H0919; FLJ46390; HGNC:6551; HMG Binding Domain; LEF1; Lef-1; lymphoid enhancer binding factor 1; lymphoid enhancer binding factor 1 short isoform; lymphoid enhancer-binding factor 1; OTTHUMP00000219736; OTTHUMP00000219737; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 16842, 51176
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid