Invitrogen™ LEF1 Monoclonal Antibody (REMB6)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
01-674-297	Invitrogen™ MA112420	250 μg
01-674-298	Invitrogen™ MA112421	100 μg

Description

A suggested positive control for this product is Jurkat cell lysate.

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: LEF1
• Concentration: 1 mg/mL
• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: P27782, Q9UJU2
• Gene ID (Entrez): 16842, 51176
• Immunogen: Full-length recombinant LEF-1 protein.
• Product Type: Antibody

• Clone: REMB6
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG1
• Target Species: Human, Mouse
• Gene: LEF1
• Gene Alias: 3000002B05; AI451430; DKFZp586H0919; FLJ46390; HGNC:6551; HMG Binding Domain; LEF1; Lef-1; lymphoid enhancer binding factor 1; lymphoid enhancer binding factor 1 short isoform; lymphoid enhancer-binding factor 1; OTTHUMP00000219736; OTTHUMP00000219737; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
• Gene Symbols: LEF1
• Primary or Secondary: Primary
• Purification Method: Ammonium sulfate precipitation