Invitrogen™ LEF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA582000

Catalog No. PIPA582000

Description

Immunogen sequence: SDVNSKQGMS RHPPAPDIPT FYPLSPGGVG QITPPLGWQG QPVYPITGGF RQPYPSSLSV DTSMSRFSHH MIPGPPGPHT TGIPHPAIVT PQVKQEHPHT DSDLMHVKPQ HEQRKEQEPK RPHIKKPLNA FMLY.

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: LEF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LEF1
• Gene Alias: 3000002B05; AI451430; DKFZp586H0919; FLJ46390; HGNC:6551; HMG Binding Domain; LEF1; Lef-1; lymphoid enhancer binding factor 1; lymphoid enhancer binding factor 1 short isoform; lymphoid enhancer-binding factor 1; OTTHUMP00000219736; OTTHUMP00000219737; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51176
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UJU2
• Gene Symbols: LEF1
• Immunogen: Recombinant protein corresponding to Human LEF1. Recombinant protein control fragment (Product #RP-100720).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov