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LEFTY AMouse anti-Human, Clone: 7C5G1H6H10, Rockland™
SDP

Catalog No. 501990518
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100 μg
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Catalog No. Quantity
50-199-0518 100 μg
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Catalog No. 50-199-0518 Supplier Rockland Immunochemicals Supplier No. 200301279
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Description

Mouse Monoclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Reacts with a 30 kDa protein corresponding to human LEFTY. No reactivity occurs against 6X HIS tag. Significant sequence homology exists between the human and mouse forms of LEFTY. Cross reactivity is expected with mouse and rat forms of the protein. Reactivity with other sources has not been determined.

Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.

Specifications

Antigen LEFTY A
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 7C5G1H6H10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene LEFTY2
Gene Accession No. O00292
Gene Alias 6030463A22Rik; AV214969; BOS_15733; EBAF; Ebaf2; endometrial bleeding associated factor; Endometrial bleeding-associated factor; LEFTA; Leftb; Left-right determination factor 2; Left-right determination factor A; Left-right determination factor B; left-right determination, factor A; Lefty2; LEFTYA; MGC46222; Protein lefty-2; Protein lefty-A; Protein lefty-B; PSEC0024; TGFB4; TGF-beta-4; Transforming growth factor beta-4
Gene Symbols LEFTY2
Host Species Mouse
Immunogen A BALB/c mouse was immunized with a recombinant form of 6X HIS tagged human LEFTY.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7044
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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