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Invitrogen™ Lefty1/Lefty2 Recombinant Rabbit Monoclonal Antibody (2Y10P2)
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Catalog No. PIMA538044
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100 μL
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PIMA538044 100 μL
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Catalog No. PIMA538044 Supplier Invitrogen™ Supplier No. MA538044
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HT-29, BxPC-3, Mouse brain, Rat brain Immunogen sequence: EMYIDLQGMK WAENWVLEPP GFLAYECVGT CRQPPEALAF KWPFLGPRQC IASETDSLPM IVSIKEGGRT RPQVVSLPNM RVQKCSCASD GALVPRRLQP.

Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lefty1/Lefty2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 2Y10P2
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LEFTY1
Gene Accession No. O00292, O75610, P57785, Q64280
Gene Alias 6030463A22Rik; AI450052; AV214969; Ebaf; Ebaf2; endometrial bleeding associated factor; endometrial bleeding-associated factor; left right determination factor 1; Lefta; LEFTB; left-right determination factor 1; Left-right determination factor 2; left-right determination factor A; Left-right determination factor B; left-right determination, factor A; left-right determination, factor B; lefty; Lefty protein; Lefty1; lefty-1; LEFTY2; LEFTYA; LEFTYB; Protein lefty-1; protein lefty-2; Protein lefty-A; protein lefty-B; PSEC0024; RGD1561867; Stimulated by retinoic acid gene 3 protein; Stra3; Tgfb4; TGF-beta-4; Transforming growth factor beta-4; UNQ278/PRO317
Gene Symbols LEFTY1, LEFTY2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 267-366 of human LEFTY1/2 (O75610).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10637, 13590, 289316, 320202, 498299, 7044
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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