Invitrogen™ Lefty1/Lefty2 Recombinant Rabbit Monoclonal Antibody (2Y10P2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538044

Catalog No. PIMA538044

Description

Positive Samples: HT-29, BxPC-3, Mouse brain, Rat brain Immunogen sequence: EMYIDLQGMK WAENWVLEPP GFLAYECVGT CRQPPEALAF KWPFLGPRQC IASETDSLPM IVSIKEGGRT RPQVVSLPNM RVQKCSCASD GALVPRRLQP.

Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.

Specifications

• Antigen: Lefty1/Lefty2
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O00292, O75610, P57785, Q64280
• Gene Symbols: LEFTY1, LEFTY2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 267-366 of human LEFTY1/2 (O75610).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 2Y10P2
• Conjugate: Unconjugated
• Gene: LEFTY1
• Gene Alias: 6030463A22Rik; AI450052; AV214969; Ebaf; Ebaf2; endometrial bleeding associated factor; endometrial bleeding-associated factor; left right determination factor 1; Lefta; LEFTB; left-right determination factor 1; Left-right determination factor 2; left-right determination factor A; Left-right determination factor B; left-right determination, factor A; left-right determination, factor B; lefty; Lefty protein; Lefty1; lefty-1; LEFTY2; LEFTYA; LEFTYB; Protein lefty-1; protein lefty-2; Protein lefty-A; protein lefty-B; PSEC0024; RGD1561867; Stimulated by retinoic acid gene 3 protein; Stra3; Tgfb4; TGF-beta-4; Transforming growth factor beta-4; UNQ278/PRO317
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10637, 13590, 289316, 320202, 498299, 7044
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov