Invitrogen™ LEFTY2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103061

Catalog No. PIPA5103061

Description

Antibody detects endogenous levels of total LEFTY2.

Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.

Specifications

• Antigen: LEFTY2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LEFTY2
• Gene Alias: 6030463A22Rik; AV214969; Ebaf; Ebaf2; endometrial bleeding associated factor; endometrial bleeding-associated factor; LEFTA; Leftb; Left-right determination factor 2; left-right determination factor A; Left-right determination factor B; left-right determination, factor A; LEFTY2; LEFTYA; MGC46222; protein lefty-2; Protein lefty-A; protein lefty-B; PSEC0024; TGFB4; TGF-beta-4; Transforming growth factor beta-4
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 289316, 320202, 7044
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O00292, P57785
• Gene Symbols: LEFTY2
• Immunogen: A synthesized peptide derived from human LEFTY2(Accession O00292), corresponding to amino acid residues V203-P253.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov