Invitrogen™ LEFTY2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521367

Catalog No. PIPA521367

Description

Recommended positive controls: A431. Predicted reactivity: Mouse (84%), Rat (83%), Pig (83%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.

Specifications

• Antigen: LEFTY2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LEFTY2
• Gene Alias: 6030463A22Rik; AV214969; Ebaf; Ebaf2; endometrial bleeding associated factor; endometrial bleeding-associated factor; LEFTA; Leftb; Left-right determination factor 2; left-right determination factor A; Left-right determination factor B; left-right determination, factor A; LEFTY2; LEFTYA; MGC46222; protein lefty-2; Protein lefty-A; protein lefty-B; PSEC0024; TGFB4; TGF-beta-4; Transforming growth factor beta-4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7044
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.01 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O00292
• Gene Symbols: LEFTY2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 25 and 366 of LEFTY2 (Uniprot ID#O00292).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov