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Invitrogen™ LEFTY2 Polyclonal Antibody
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Catalog No. PIPA5109905
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100 μL
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PIPA5109905 100 μL
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Catalog No. PIPA5109905 Supplier Invitrogen™ Supplier No. PA5109905
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VRAQYVVLLR RSHGDRSRGK RFSQSFREVA GRFLASEAST HLLVFGMEQR LPPNSELVQA VLRLFQEPVP KAALHRHGRL SPRSAQARVT VEWLRVRDDG SNRTSLIDSR LVSVHESGWK AFDVTEAVNF WQQLSRPRQP LLLQVSVQRE HLGPLASGAH KLVRFASQGA PAGLGEPQLE LHTLDLRDYG AQGDCDPEAP MTEGTRCCRQ EMYIDLQGMK WAKNWVLEPP GFLAYECVGT CQQPPEALAF NWPFLGPRQC IASETASLPM IVSIKEGGRT RPQVVSLPNM RVQKCSCASD GALVPRRLQP.

Left-right determination factor 1 and 2 (Lefty1/2) belong to the TGF-beta superfamily of proteins and are responsible for determination of left-right positioning of visceral organs during embryogenesis. Lefty1 acts as a regulator of Lefty2 and NODAL as the lack of the former resulted in bilateral expression of nodal, lefty2 and Pitx2 (a homeobox gene normally expressed on the left side and blocks the signal for leftness). Lefty2 may play a role in endometrial bleeding.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LEFTY2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.56 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LEFTY2
Gene Accession No. O00292, P57785
Gene Alias 6030463A22Rik; AV214969; Ebaf; Ebaf2; endometrial bleeding associated factor; endometrial bleeding-associated factor; LEFTA; Leftb; Left-right determination factor 2; left-right determination factor A; Left-right determination factor B; left-right determination, factor A; LEFTY2; LEFTYA; MGC46222; protein lefty-2; Protein lefty-A; protein lefty-B; PSEC0024; TGFB4; TGF-beta-4; Transforming growth factor beta-4
Gene Symbols LEFTY2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 57-366 of human LEFTY2 (NP_003231.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 320202, 7044
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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