Invitrogen™ LEO1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531651

Catalog No. PIPA531651

Description

Recommended positive controls: A431, Jurkat. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (93%), Xenopus laevis (96%), Chicken (94%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Specifications

• Antigen: LEO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Leo1
• Gene Alias: Gm185; Leo1; LEO1 homolog, Paf1/RNA polymerase II complex component; Leo1 Paf1/RNA polymerase II complex component; Leo1, Paf1/RNA polymerase II complex component, homolog; Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); RDL; Replicative senescence down-regulated leo1-like protein; RNA polymerase-associated protein LEO1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 123169
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8WVC0
• Gene Symbols: Leo1
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human LEO1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG