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Invitrogen™ LEPREL1 Polyclonal Antibody
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Catalog No. PIPA596918
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100 μL
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PIPA596918 100 μL
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Catalog No. PIPA596918 Supplier Invitrogen™ Supplier No. PA596918
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IRYGGRQDEN RVPSGVNVEG AEVHGFSMGK KLSPKIDRDL REGGPLLYEN ITFVYNSEQL NGTQRVLLDN VLSEEQCREL HSVASGIMLV GDGYRGKTSP HTPNEKFEGA TVLKALKSGY EGRVPLKSAR LFYDISEKAR RIVESYFMLN STLYFSYTHM VCRTALSGQQ DRRNDLSHPI HADNCLLDPE ANECWKEPPA YTFRDYSALL YMNDDFEGGE FIFTEMDAKT VTASIKPKCG RMISFSSGGE NPHGVKAVTK GKRCAVALWF TLDPLYRELE RIQADEVIAI LDQEQQGKHE L; Positive Samples: NCI-H460; Cellular Location: Endoplasmic reticulum, Golgi apparatus.

This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LEPREL1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene P3h2
Gene Accession No. Q4KLM6, Q8CG71, Q8IVL5
Gene Alias 4832416N06; AW553532; leprecan-like 1; leprecan-like protein 1; Leprel1; MCVD; Mlat4; myxoid liposarcoma associated protein 4; myxoid liposarcoma-associated protein 4; P3h2; procollagen-proline 3-dioxygenase 2; prolyl 3-hydroxylase 2; prolyl 3-hydroxylase 3
Gene Symbols P3h2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human LEPREL1 (NP_0606622).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 210530, 288016, 55214
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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