Invitrogen™ LEPREL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596914

Catalog No. PIPA596914

Description

Immunogen sequence: DAAGAGARSG YRGRRSPHTP HERFEGLTVL KAAQLARAGT VGSQGAKLLL EVSERVRTLT QAYFSPERPL HLSFTHLVCR SAIEGEQEQR MDLSHPVHAD NCVLDPDTGE CWREPPAYTY RDYSGLLYLN DDFQGGDLFF TEPNALTVTA RVRPRCGRLV AFSSGVENPH GVWAVTRGRR CALALWHTWA PEHREQEWIE AKELLQESQE EEEEEEEEMP SKDPSPEPPS RRHQRVQDKT GRAPRVREEL; Positive Samples: 22Rv1, NIH/3T3, Mouse skeletal muscle; Cellular Location: Endoplasmic reticulum.

The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.

Specifications

• Antigen: LEPREL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: P3h3
• Gene Alias: BC016431; gene rich cluster, B; GRCB; HSU47926; leprecan-like 2; leprecan-like protein 2; LEPREL2; P3H3; procollagen-proline 3-dioxygenase; prolyl 3-hydroxylase 3; Protein B
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10536, 14789
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.86 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8CG70, Q8IVL6
• Gene Symbols: P3h3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 487-736 of human LEPREL2 (NP_0550772).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov