Invitrogen™ LPXN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579610

Catalog No. PIPA579610

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Raji whole cell, human PC-3 whole cell, human U87 whole cell, human MDA-MB-453 whole cell, mouse RAW2647 whole cell. Flow: Raji cell.

The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: LPXN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LPXN
• Gene Alias: 4933402K05Rik; A530083L21Rik; AV278559; LDLP; LDPL; Leupaxin; LPXN
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107321, 9404
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: O60711, Q99N69
• Gene Symbols: LPXN
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Leupaxin (115-129aa KKHLPDKQDHKASLD).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG