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  5. Tocris Bioscience™ Levetiracetam

Tocris Bioscience™ Levetiracetam
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Catalog No. 283910
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28-391-0 10 mg
28-395-0 50 mg
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Catalog No. 28-391-0 Supplier Tocris Bioscience™ Supplier No. 2839/10
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Description

Antiepileptic; binds SV2A

Levetiracetam is an antiepileptic that displays distinctive properties from conventional antiepileptic drugs. Displays potent seizure protection in animal models of chronic epilepsy but lacks activity in acute seizure models. Binds synaptic vesicle protein 2A (SV2A) and inhibits Na+-dependent Cl-/HCO3- exchange. In a mouse model of Alzheimer's disease, Levetiracetam rescues levels of presynaptic vesicle fusion and neurotransmitter release, reduces Aβ42 and APP levels and decreases deposits of amyloid plaque; in vitro Levetiracetam inhibits Aβ-induced glutamate from astrocytes.

Chemical Identifiers

CAS 102767-28-2
Molecular Formula C8H14N2O2

Specifications

Quantity 10 mg
Formula Weight 170.21
Purity >99%
Molecular Weight (g/mol) 170.21
Chemical Name or Material Levetiracetam

Safety and Handling

Recommended Storage Store at Room Temperature
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