Invitrogen™ Levodopa Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119575

Catalog No. PIPA5119575

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Levodopa, also known as L-DOPA, is the most widely used drug for the symptomatic treatment of Parkinson's disease, serving as the gold standard for managing the disease's motor symptoms. It functions as a precursor to dopamine, which is deficient in patients with Parkinson's disease due to the degeneration of dopaminergic neurons in the substantia nigra. Once ingested, levodopa crosses the blood-brain barrier and is converted to dopamine, thereby alleviating symptoms such as bradykinesia, rigidity, and tremor. The pharmacokinetics and pharmacodynamics of levodopa have been extensively studied, with various formulations developed to optimize its absorption and reduce side effects. Despite its efficacy, long-term use of levodopa can lead to complications, including motor fluctuations and dyskinesias.

Specifications

• Antigen: Levodopa
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: l-3,4-dihydroxyphenylalanine; L-DOPA
• Immunogen: Levodopa (L-DOPA).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Target Molecule: Chemical

• Applications: Dot Blot, ELISA
• Concentration: 0.35 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Target Species: Chemical
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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