LexA DNA-binding Domain Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Supplier:  Active Motif 39184

Catalog No. 50-199-3943

Description

E. coli LexA protein inhibits the transcription of the genes belonging to the SOS regulon that are related to DNA repair and cell division by recognizing and binding to the SOS-box sequence. LexA‘s self-protease activity is promoted by RecA protein which, responding to DNA damage, is activated by its binding to single-strand DNA accumulated in the cells. It is cleaved into two fragments and loses its function as a repressor. As the result, the expression of genes belonging to the SOS regulon is induced, and mutagenic activity in the cells are enhanced.

Specifications

• Antigen: LexA DNA-binding Domain
• Classification: Polyclonal
• Conjugate: Unconjugated
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
• Immunogen: This LexA DNA-binding Domain antibody was raised against recombinant protein corresponding to full-length E. coli LexA.
• Regulatory Status: RUO
• Target Species: Yeast
• Product Type: Antibody
• Isotype: IgG