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Invitrogen™ LexA Polyclonal Antibody
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Catalog No. PIPA14966
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50 μL
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PIPA14966 50 μL
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Catalog No. PIPA14966 Supplier Invitrogen™ Supplier No. PA14966
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Description

Rabbit Polyclonal Antibody

PA1-4966 detects LexA protein in E.coli and yeast samples. PA1-4966 has been successfully used in Western blot, immunoprecipitation and immunohistochemical procedures. It is specific for the ~23 kDa LexA protein. PA1-4966 immunogen is a highly purified recombinant full size LexA protein. Store at -20°C.

E. coli LexA protein inhibits the transcription of the genes belonging to the SOS regulon that are related to DNA repair and cell division by recognizing and binding to the SOS-box sequence. LexA's self-protease activity is promoted by RecA protein which, responding to DNA damage, is activated by its binding to single-strand DNA accumulated in the cells. It is cleaved into two fragments and loses its function as a repressor. As the result, the expression of genes belonging to the SOS regulon is induced, and mutagenic activity in the cells are enhanced.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LexA
Applications ChIP Assay, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.05% sodium azide
Host Species Rabbit
Immunogen Full size LexA recombinant protein.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Yeast, Bacteria
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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