Invitrogen™ LFNG Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542669

Catalog No. PIPA542669

Description

Peptide sequence: LSEYFSLLTR ARRDAGPPPG AAPRPADGHP RPLAEPLAPR DVFIAVKTTK Sequence homology: Cow: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 100%.

LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).

Specifications

• Antigen: LFNG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LFNG
• Gene Alias: AW061165; beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; LFNG; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; lunatic fringe; lunatic fringe gene homolog; MGC128664 protein; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; SCDO3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3955
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8NES3
• Gene Symbols: LFNG
• Immunogen: Synthetic peptide directed towards the N-terminal of human LFNG (aa 74-123).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG