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Invitrogen™ LFNG Polyclonal Antibody
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Catalog No. PIPA584802
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100 μL
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Catalog No. Quantity
PIPA584802 100 μL
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Catalog No. PIPA584802 Supplier Invitrogen™ Supplier No. PA584802
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TKKFHRARLD LLLETWISRH KEMTFIFTDG EDEALARHTG NVVITNCSAA H Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 88%.

LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).
TRUSTED_SUSTAINABILITY

Specifications

Antigen LFNG
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LFNG
Gene Accession No. Q8NES3
Gene Alias AW061165; beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; LFNG; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; lunatic fringe; lunatic fringe gene homolog; MGC128664 protein; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; SCDO3
Gene Symbols LFNG
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LFNG. Recombinant protein control fragment (Product #RP-103673).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3955
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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