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Tocris Bioscience™ LG 100268
GREENER_CHOICE

Catalog No. 592025
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Potent and selective RXR agonist; also activates RXR/PPARγ heterodimers

LG 100268 is a potent and selective retinoid X receptor (RXR) agonist (EC50 = 4 nM). Displays >1000-fold selectivity for RXR over RAR. Activates RXR homodimers to induce transcriptional activation. Induces tissue transglutaminase (TGase) activity in HL-60 human promyelocytic leukemia cell line. Also activates RXR/PPARγ heterodimers.

Specifications

Chemical Name or Material 6-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-pyridinecarboxylic acid
CAS 153559-76-3
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C24H29NO2
Formula Weight Observed MW: 363.49
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