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Invitrogen™ LGI1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ 720377
Description
This antibody is predicted to react with Monkey, Cat, Horse, Sheep.
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.
Specifications
LGI1 | |
Polyclonal | |
Unconjugated | |
LGI1 | |
ADLTE; ADPAEF; ADPEAF; BB130740; EPITEMPIN; Epitempin 1; Epitempin-1; EPT; ETL1; IB1099; leucine rich glioma inactivated 1; leucine-rich glioma inactivated 1; leucine-rich glioma-inactivated protein 1; leucine-rich repeat LGI family, member 1; leucine-rich, glioma inactivated 1; LGI1; OTTHUMP00000020121; OTTHUMP00000020122; UNQ775/PRO1569 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
252892, 56839, 9211 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4 | |
O95970, Q8K4Y5, Q9JIA1 | |
LGI1 | |
Peptides corresponding to human LGI1 [1) aa201-aa220 2) aa323-aa341]. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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