LGI1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-8014	150 μL

Catalog No. 50-172-8014 Supplier Proteintech Group Inc Supplier No. 124831AP150UL

Description

Rabbit Polyclonal Antibody

The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodomit lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predomit auditory symptoms. Two isoforms of LGI1 are known to exist.

Specifications

• Antigen: LGI1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.22 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: LGI1
• Gene Accession No.: O95970, Q8K4Y5, Q9JIA1
• Gene Alias: EPITEMPIN, Epitempin 1, EPT, ETL1, IB1099, LGI1
• Gene Symbols: Lgi1
• Host Species: Rabbit
• Immunogen: LGI1 Fusion Protein Ag3184
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 252892, 56839, 9211
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG