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Invitrogen™ LGI2 Polyclonal Antibody
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Catalog No. PIPA520493
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100 μg
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Catalog No. Quantity
PIPA520493 100 μg
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Catalog No. PIPA520493 Supplier Invitrogen™ Supplier No. PA520493
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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse liver tissue lysate. PA5-20493 can be used with blocking peptide PEP-0613.

The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LGI2
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Lgi2
Gene Accession No. Q8K4Z0, Q8N0V4
Gene Alias Kiaa1916; leucine rich repeat LGI family member 2; leucine-rich glioma-inactivated protein 2; Leucine-rich repeat LGI family member 2; leucine-rich repeat LGI family, member 2; leucine-rich, glioma inactivated 2; LGI1-like protein 2; Lgi2; LGIL2; mKIAA1916
Gene Symbols Lgi2
Host Species Rabbit
Immunogen a 10 amino acid peptide from near the center of human LGI2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246316, 55203
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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