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Invitrogen™ LGI2 Polyclonal Antibody
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Catalog No. PIPA553555
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100 μL
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PIPA553555 100 μL
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Catalog No. PIPA553555 Supplier Invitrogen™ Supplier No. PA553555
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DLTHLSLANN HIKALPRDVF SDLDSLIELD LRGNKFECDC KAKWLYLWLK MTNSTVSDVL CIGPPEYQEK KLNDVTSFDY ECTTTDFVVH QTLPYQSVSV DTFNSKNDVY VAIAQPSMEN CMVLEW Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.

The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LGI2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Lgi2
Gene Accession No. Q8N0V4
Gene Alias Kiaa1916; leucine rich repeat LGI family member 2; leucine-rich glioma-inactivated protein 2; Leucine-rich repeat LGI family member 2; leucine-rich repeat LGI family, member 2; leucine-rich, glioma inactivated 2; LGI1-like protein 2; Lgi2; LGIL2; mKIAA1916
Gene Symbols Lgi2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LGI2. Recombinant protein control fragment (Product #RP-90365).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55203
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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